verrucosidin
naturalproductmech:mibig-7e0b3771ba MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | JSVLNARHSWZARV-FOOXNAEUSA-N |
|---|---|
| SMILES | COC1=C(C)C(=O)OC([C@]2(C)O[C@H]2/C(C)=C/C(C)=C/[C@]2(C)O[C@H](C)[C@@]3(C)O[C@@H]23)=C1C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:6437365, npatlas:NPA032775 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium polonicum NCBITaxon:60169 |
BGC_CHARACTERIZED | mibig:BGC0002745 | DOI:10.1016/j.tox.2006.11.049 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Talaromyces verruculosus NCBITaxon:198730 |
LOTUS | DOI:10.1021/NP50055A008 |
| Penicillium aurantiogriseum NCBITaxon:36655 |
LOTUS | DOI:10.1039/C39830000544 |
| Penicillium verrucosum NCBITaxon:60171 |
LOTUS | DOI:10.1039/C39830000544 |
| Penicillium polonicum NCBITaxon:60169 |
LOTUS | DOI:10.3389/FMICB.2021.660871 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002745 | Penicillium polonicum NCBITaxon:60169 |
CLUSTER_DEMONSTRATED | genbank:MDYM01000002.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002745 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/verrucosidin.yaml, which is generated from the committed inventories. Neither is edited by hand.