NaturalProductMech

WS 79089A

naturalproductmech:mibig-28490231db MINTED SEEDED

Structure

Standard InChIKeyHRWPMELFEHBAIH-UHFFFAOYSA-N
SMILESCC1CC2=C(C(=C3C(=C2)CC(C4=C3C(=C5C(=C4OC)C(=O)C6=C(C5=O)C=CC=C6O)O)O)O)C(=O)O1
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA008064, npatlas:NPA08064

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptosporangium roseum DSM 43021
NCBITaxon:479432
BGC_CHARACTERIZED mibig:BGC0002732 PMID:32632478
Streptosporangium sp. FXJ7.131
NCBITaxon:683272
SOURCE_ASSERTION mibig:BGC0001376 PMID:26754814

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptosporangium
NCBITaxon:2000
LOTUS DOI:10.1007/S00253-015-7248-Z
Streptosporangium
NCBITaxon:2000
LOTUS DOI:10.7164/ANTIBIOTICS.47.619

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002732 Streptosporangium roseum DSM 43021
NCBITaxon:479432
CLUSTER_DEMONSTRATED genbank:CP001814.1
mibig:BGC0001376 Streptosporangium sp. FXJ7.131
NCBITaxon:683272
CLUSTER_UNSTATED genbank:KT713752.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001376, BGC0002732. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002732MIBIG3
BGC0001376MIBIG5

This page is generated from data/natural_products/polyketides/ws-79089a.yaml, which is generated from the committed inventories. Neither is edited by hand.