4-hydroxy-3-prenylbenzoic acid

naturalproductmech:mibig-b4ad51fa2f REVIEW_NEEDED SEEDED

Grounding review: This structure matches more than one 3-star ChEBI entry: CHEBI:1845, CHEBI:31111. ChEBI keeps such entries separate on purpose — a compound and its zwitterion share an InChIKey — so the identity is not picked here. A curator decides which term this record is.

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKey	LBSJJNAMGVDGCU-UHFFFAOYSA-N
SMILES	C/C(C)=C/CC1=C(O)C=CC(C(O)=O)=C1
Stereochemistry	fully defined

Filing pathway

Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Biscogniauxia sp. NCBITaxon:1896107	SOURCE_ASSERTION	mibig:BGC0002290	PMID:32364293

Occurrences 9

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Piper hispidum NCBITaxon:130401	LOTUS	DOI:10.1002/CHIN.200541203
Rubia yunnanensis NCBITaxon:1650721	LOTUS	DOI:10.1021/NP2002918
Rubia yunnanensis NCBITaxon:1650721	CHEBI	PMID:21973054
Curvularia fallax NCBITaxon:215128	LOTUS	DOI:10.1016/0031-9422(90)85203-R
Prunus dulcis NCBITaxon:3755	LOTUS	DOI:10.1021/JF0110194
Prunus avium NCBITaxon:42229	LOTUS	DOI:10.1021/JF0110194
Anodendron affine NCBITaxon:582712	LOTUS	DOI:10.1248/YAKUSHI1947.92.11_1410
Zanthoxylum wutaiense NCBITaxon:697043	LOTUS	DOI:10.1021/NP700719E
Ozothamnus obcordatus NCBITaxon:857094	LOTUS	DOI:10.1016/0031-9422(91)85127-L

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0002290	Biscogniauxia sp. NCBITaxon:1896107	CLUSTER_DEMONSTRATED	genbank:MT109335.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Explore across X-Mech

AntibioticMech (4-hydroxy-3-prenylbenzoic acid) ↗ MediaIngredientMech (naturalproductmech:mibig-b4ad51fa2f) ↗ TaxonMech: Biscogniauxia sp. (NCBITaxon:1896107) ↗ PathwayMech (mibig:BGC0002290) ↗

Provenance

Source concept	Source	Version
BGC0002290	MIBIG	2
CHEBI:1845	CHEBI	3-star
CHEBI:31111	CHEBI	3-star

This page is generated from data/natural_products/shikimates_and_phenylpropanoids/4-hydroxy-3-prenylbenzoic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.