atromentin
CHEBI:149660 EXACT SEEDED antibacterial
A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione which is substituted by a 4-hydroxyphenyl group at positions 3 and 6. It is a mushroom pigment isolated from several fungi species and acts as a smooth muscle stimulant, and exhibits anticoagulant, antibacterial and antineoplastic properties.
Structure
| Standard InChIKey | FKQQKMGWCJGUCS-UHFFFAOYSA-N |
|---|---|
| SMILES | C1=CC(=CC=C1C2=C(C(=O)C(=C(C2=O)O)C3=CC=C(C=C3)O)O)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA018419 |
Filing pathway
Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Suillus grevillei NCBITaxon:5382 |
SOURCE_ASSERTION | mibig:BGC0002277 | PMID:22730234 |
Occurrences 16
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Hydnellum diabolus NCBITaxon:176618 |
LOTUS | DOI:10.1002/JPS.2600540714 |
| Hydnellum diabolus NCBITaxon:176618 |
CHEBI | PMID:5862512 |
| Omphalotus subilludens NCBITaxon:210149 |
LOTUS | DOI:10.1002/JPS.2600601134 |
| Clitocybe subilludens NCBITaxon:210149 |
CHEBI | PMID:4332377 |
| Clitocybe subilludens NCBITaxon:210149 |
CHEBI | PMID:5815216 |
| Fungi NCBITaxon:4751 |
CHEBI | PMID:17323650 |
| Suillus bovinus NCBITaxon:48563 |
LOTUS | DOI:10.1039/J39690002398 |
| Hypoxylon fendleri NCBITaxon:558530 |
CHEBI | PMID:28384525 |
| Hypoxylon fendleri NCBITaxon:558530 |
CHEBI | PMID:31476402 |
| Thelephora aurantiotincta NCBITaxon:654496 |
LOTUS | DOI:10.1002/CHIN.200349210 |
| Thelephora aurantiotincta NCBITaxon:654496 |
LOTUS | DOI:10.1016/S0031-9422(03)00220-6 |
| Thelephora aurantiotincta NCBITaxon:654496 |
CHEBI | PMID:12895540 |
| Tapinella atrotomentosa NCBITaxon:72122 |
LOTUS | DOI:10.1002/JLAC.198919890228 |
| Tapinella atrotomentosa NCBITaxon:72122 |
LOTUS | DOI:10.1002/JPS.2600601013 |
| Paxillus panuoides NCBITaxon:80604 |
CHEBI | PMID:5166969 |
| Suillus grevillei NCBITaxon:5382 |
LOTUS | DOI:10.1002/CBIC.201200187 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002277 | Suillus grevillei NCBITaxon:5382 |
CLUSTER_DEMONSTRATED | genbank:JQ681152.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:149660 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002277 | MIBIG | 2 |
| CHEBI:149660 | CHEBI | 3-star |
This page is generated from data/natural_products/shikimates_and_phenylpropanoids/atromentin.yaml, which is generated from the committed inventories. Neither is edited by hand.