NaturalProductMech

legioliulin

CHEBI:156300 EXACT SEEDED

A member of the class of isocoumarins that is 8-hydroxy-1H-isochromen-1-one substituted by a (1E,3E)-4-phenylbuta-1,3-dien-1-yl group at position 3. It is a fluorophore responsible for the blue-white autofluorescence in Legionella dumoffii.

Structure

Standard InChIKeyIFFMOWIJJAFQJN-HINBXAKRSA-N
SMILESOC1=C2C(=O)OC(\C=C\C=C\C3=CC=CC=C3)=CC2=CC=C1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA0480

Filing pathway

Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Legionella parisiensis
NCBITaxon:45071
BGC_CHARACTERIZED mibig:BGC0000180 PMID:23821465

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fluoribacter dumoffii
NCBITaxon:463
LOTUS DOI:10.1016/J.BBRC.2004.08.180
Fluoribacter dumoffii
NCBITaxon:463
CHEBI PMID:15381093
Legionella parisiensis
NCBITaxon:45071
LOTUS DOI:10.1002/CBIC.201300373
Legionella parisiensis
NCBITaxon:45071
CHEBI PMID:23821465

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000180 Legionella parisiensis
NCBITaxon:45071
CLUSTER_DEMONSTRATED genbank:KM222819.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000180MIBIG5
CHEBI:156300CHEBI3-star

This page is generated from data/natural_products/shikimates_and_phenylpropanoids/legioliulin.yaml, which is generated from the committed inventories. Neither is edited by hand.