(−)-microperfuranone
CHEBI:64974 EXACT SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A butenolide that is furan-2(5H)-one which is substituted by a phenyl group at position 3, a benzyl group at position 4, and a hydroxy group at position 5 (the (−)-enantiomer). A secondary metabolite obtained from Aspergillus nidulans.
Structure
| Standard InChIKey | MFURXTOJWOOSEM-UHFFFAOYSA-N |
|---|---|
| SMILES | OC1OC(=O)C(=C1CC1=CC=CC=C1)C1=CC=CC=C1 |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA016720 |
Filing pathway
Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
SOURCE_ASSERTION | mibig:BGC0001668 | PMID:22627757 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aspergillus nidulans NCBITaxon:162425 |
LOTUS | DOI:10.1007/S00253-012-4098-9 |
| Aspergillus nidulans NCBITaxon:162425 |
LOTUS | DOI:10.1248/CPB.54.550 |
| Aspergillus quadrilineatus NCBITaxon:41735 |
LOTUS | DOI:10.1248/CPB.54.550 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001668 | Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
CLUSTER_UNSTATED | genbank:BN001306.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001668 | MIBIG | 4 |
| CHEBI:64974 | CHEBI | 3-star |
This page is generated from data/natural_products/shikimates_and_phenylpropanoids/microperfuranone.yaml, which is generated from the committed inventories. Neither is edited by hand.