NaturalProductMech

paerucumarin

CHEBI:140649 EXACT SEEDED

A hydroxycoumarin that is coumarin substituted by an isocyano group at position 3 and hydroxy groups at positions 6 and 7.

Structure

Standard InChIKeyPBXVYKHISUQHKY-UHFFFAOYSA-N
SMILESOC1=C(O)C=C2C=C([N+]#[C-])C(=O)OC2=C1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA018070

Filing pathway

Shikimates and phenylpropanoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pseudomonas aeruginosa PAO1
NCBITaxon:208964
SOURCE_ASSERTION mibig:BGC0000923 PMID:10383985

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pseudomonas aeruginosa
NCBITaxon:287
LOTUS DOI:10.1007/S12275-016-5645-3
Pseudomonas aeruginosa
NCBITaxon:287
LOTUS DOI:10.1016/J.MICPATH.2018.12.001
Pseudomonas aeruginosa
NCBITaxon:287
LOTUS DOI:10.1128/JB.00801-08
Pseudomonas aeruginosa
NCBITaxon:287
LOTUS DOI:10.1128/JB.181.13.4118-4124.1999
Pseudomonas aeruginosa
NCBITaxon:287
LOTUS DOI:10.1371/JOURNAL.PONE.0062735
Pseudomonas aeruginosa
NCBITaxon:287
CHEBI PMID:18689486

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000923 Pseudomonas aeruginosa PAO1
NCBITaxon:208964
CLUSTER_UNSTATED genbank:AF002222.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000923MIBIG3
CHEBI:140649CHEBI3-star

This page is generated from data/natural_products/shikimates_and_phenylpropanoids/paerucumarin.yaml, which is generated from the committed inventories. Neither is edited by hand.