brevione E
naturalproductmech:mibig-6295b1addd MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | JNDQPDZQDHPEAE-WTAVCZOCSA-N |
|---|---|
| SMILES | CC1=C[C@](O2)([H])[C@@]3([H])[C@]4([C@]15[C@@](C/C(O5)=C(C)\C(C)=O)([H])O[C@H]4OC(C)=O)CC[C@]6([H])[C@]3(C)[C@]2([H])CC(C=C6C)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA019168, pubchem:101092881 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium bialowiezense CBS 227.28 NCBITaxon:293381 |
SOURCE_ASSERTION | mibig:BGC0002759 | DOI:10.1002/anie.202210938 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002759 | Penicillium bialowiezense CBS 227.28 NCBITaxon:293381 |
CLUSTER_DEMONSTRATED | genbank:LC719581.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002759 | MIBIG | 2 |
This page is generated from data/natural_products/terpenoids/brevione-e.yaml, which is generated from the committed inventories. Neither is edited by hand.