NaturalProductMech

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carotenoid

naturalproductmech:mibig-8426508598 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyMQXYWDPDLKUSFB-HOOXQTDMSA-N
SMILESC[C@H](CCCCC(C)CCC[C@@H](C)CCCC(C)CCC=C(C)C)CCC[C@H](C)CCC[C@H](C)CCCC(C)(C)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:446841

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 16

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces avermitilis
NCBITaxon:33903		 SOURCE_ASSERTION mibig:BGC0000633 PMID:11572948
Brevundimonas sp. SD212
NCBITaxon:1113698		 SOURCE_ASSERTION mibig:BGC0000634 PMID:16085816
Paracoccus sp. N81106
NCBITaxon:81397		 SOURCE_ASSERTION mibig:BGC0000635 PMID:7733978
Brevibacterium linens
NCBITaxon:1703		 SOURCE_ASSERTION mibig:BGC0000636 PMID:10821176
Corynebacterium glutamicum
NCBITaxon:1718		 SOURCE_ASSERTION mibig:BGC0000637 PMID:11432736
Pantoea ananatis
NCBITaxon:553		 SOURCE_ASSERTION mibig:BGC0000638 PMID:2254247
Enterobacteriaceae bacterium DC260
NCBITaxon:338904		 SOURCE_ASSERTION mibig:BGC0000639 PMID:16332796
Enterobacteriaceae bacterium DC404
NCBITaxon:338905		 SOURCE_ASSERTION mibig:BGC0000640 PMID:16332796
Enterobacteriaceae bacterium DC416
NCBITaxon:338906		 SOURCE_ASSERTION mibig:BGC0000641 PMID:16332796
Enterobacteriaceae bacterium DC413
NCBITaxon:338907		 SOURCE_ASSERTION mibig:BGC0000642 PMID:16332796
Brevundimonas vesicularis
NCBITaxon:41276		 SOURCE_ASSERTION mibig:BGC0000643 PMID:16781830
Dietzia sp. CQ4
NCBITaxon:370437		 SOURCE_ASSERTION mibig:BGC0000644 PMID:17008032
Halobacillus halophilus DSM 2266
NCBITaxon:866895		 SOURCE_ASSERTION mibig:BGC0000645 PMID:18820900
Rhodobacter sphaeroides
NCBITaxon:1063		 SOURCE_ASSERTION mibig:BGC0000647 PMID:8021167
Myxococcus xanthus
NCBITaxon:34		 SOURCE_ASSERTION mibig:BGC0000648 PMID:7588751
Streptomyces griseus subsp. griseus NBRC 13350
NCBITaxon:455632		 SOURCE_ASSERTION mibig:BGC0000649 PMID:11200234

Occurrences 9

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Halobacillus halophilus
NCBITaxon:1570		 LOTUS DOI:10.1007/S00203-008-0431-1
Dietzia
NCBITaxon:37914		 LOTUS DOI:10.1016/J.GENE.2006.08.006
Brevundimonas
NCBITaxon:41275		 LOTUS DOI:10.1128/AEM.71.8.4286-4296.2005
Enterobacteriaceae
NCBITaxon:543		 LOTUS DOI:10.1128/AEM.71.12.8141-8146.2005
Rhodobacter sphaeroides
NCBITaxon:1063		 LOTUS DOI:10.1128/JB.176.13.3859-3869.1994
Brevibacterium linens
NCBITaxon:1703		 LOTUS DOI:10.1007/S004380051186
Streptomyces avermitilis
NCBITaxon:33903		 LOTUS DOI:10.1073/PNAS.211433198
Myxococcus xanthus
NCBITaxon:34		 LOTUS DOI:10.1111/J.1432-1033.1995.238_1.X
Brevundimonas vesicularis
NCBITaxon:41276		 LOTUS DOI:10.1016/J.GENE.2006.04.017

Biosynthetic gene clusters 16

AccessionHostLocus evidenceGenome
mibig:BGC0000633 Streptomyces avermitilis
NCBITaxon:33903 		CLUSTER_UNSTATED genbank:AB070934.1
mibig:BGC0000634 Brevundimonas sp. SD212
NCBITaxon:1113698 		CLUSTER_UNSTATED genbank:AB181388.1
mibig:BGC0000635 Paracoccus sp. N81106
NCBITaxon:81397 		CLUSTER_UNSTATED genbank:AB206672.1
mibig:BGC0000636 Brevibacterium linens
NCBITaxon:1703 		CLUSTER_UNSTATED genbank:AF139916.1
mibig:BGC0000637 Corynebacterium glutamicum
NCBITaxon:1718 		CLUSTER_UNSTATED genbank:AF159510.1
mibig:BGC0000638 Pantoea ananatis
NCBITaxon:553 		CLUSTER_UNSTATED genbank:D90087.2
mibig:BGC0000639 Enterobacteriaceae bacterium DC260
NCBITaxon:338904 		CLUSTER_UNSTATED genbank:DQ090833.1
mibig:BGC0000640 Enterobacteriaceae bacterium DC404
NCBITaxon:338905 		CLUSTER_UNSTATED genbank:DQ090834.1
mibig:BGC0000641 Enterobacteriaceae bacterium DC416
NCBITaxon:338906 		CLUSTER_UNSTATED genbank:DQ090835.1
mibig:BGC0000642 Enterobacteriaceae bacterium DC413
NCBITaxon:338907 		CLUSTER_UNSTATED genbank:DQ090836.1
mibig:BGC0000643 Brevundimonas vesicularis
NCBITaxon:41276 		CLUSTER_UNSTATED genbank:DQ309446.1
mibig:BGC0000644 Dietzia sp. CQ4
NCBITaxon:370437 		CLUSTER_UNSTATED genbank:DQ369754.1
mibig:BGC0000645 Halobacillus halophilus DSM 2266
NCBITaxon:866895 		CLUSTER_UNSTATED genbank:FJ040212.1
mibig:BGC0000647 Rhodobacter sphaeroides
NCBITaxon:1063 		CLUSTER_UNSTATED genbank:S71770.1
mibig:BGC0000648 Myxococcus xanthus
NCBITaxon:34 		CLUSTER_UNSTATED genbank:Z21955.2
mibig:BGC0000649 Streptomyces griseus subsp. griseus NBRC 13350
NCBITaxon:455632 		CLUSTER_UNSTATED genbank:AF272737.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 16 producers (0 causal) 9 cited occurrences BIOSYNTHETIC LOCUS 16 gene clusters 0 curated pathway steps NATURAL PRODUCT carotenoid naturalproductmech:mibig-8426508598 Terpenoids TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

Explore across X-Mech

AntibioticMech (carotenoid) ↗ MediaIngredientMech (naturalproductmech:mibig-8426508598) ↗ TaxonMech: Streptomyces avermitilis (NCBITaxon:33903) ↗ TaxonMech: Brevundimonas sp. SD212 (NCBITaxon:1113698) ↗ TaxonMech: Paracoccus sp. N81106 (NCBITaxon:81397) ↗ TaxonMech: Brevibacterium linens (NCBITaxon:1703) ↗ PathwayMech (mibig:BGC0000633) ↗ PathwayMech (mibig:BGC0000634) ↗ PathwayMech (mibig:BGC0000635) ↗

Open questions 2

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000633, BGC0000634, BGC0000635, BGC0000636, BGC0000637, BGC0000638, BGC0000639, BGC0000640, BGC0000641, BGC0000642, BGC0000643, BGC0000644, BGC0000645, BGC0000647, BGC0000648, BGC0000649. Confirm they describe the same compound rather than an upstream cross-reference error.

curator-carotenoid-generic-class-structure-collapse — Which individual products and experimental contexts belong to the sixteen generic carotenoid source concepts?

Provenance

Source conceptSourceVersion
BGC0000633MIBIG3
BGC0000634MIBIG3
BGC0000635MIBIG3
BGC0000636MIBIG3
BGC0000637MIBIG3
BGC0000638MIBIG3
BGC0000639MIBIG3
BGC0000640MIBIG3
BGC0000641MIBIG3
BGC0000642MIBIG3
BGC0000643MIBIG3
BGC0000644MIBIG3
BGC0000645MIBIG3
BGC0000647MIBIG3
BGC0000648MIBIG3
BGC0000649MIBIG3

This page is generated from data/natural_products/terpenoids/carotenoid-2.yaml, which is generated from the committed inventories. Neither is edited by hand.