NaturalProductMech

conidiogenone

CHEBI:189095 EXACT SEEDED

A diterpenoid with formula C20H32O2. It is isolated from Penicillium cyclopium and exhibits potent conidiation inducing activity.

Structure

Standard InChIKeyVXPSMCORCRBNAO-TYVLEIALSA-N
SMILESC[C@H]1[C@@H](CC(=O)[C@]2([C@@]13C[C@]4(CCC([C@H]4[C@@H]3CC2)(C)C)C)C)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA017609

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Penicillium rubens Wisconsin 54-1255
NCBITaxon:500485
SOURCE_ASSERTION mibig:BGC0002320 PMID:30343633

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Penicillium aurantiogriseum
NCBITaxon:36655
LOTUS DOI:10.1016/S0040-4039(02)01493-4
Penicillium aurantiogriseum
NCBITaxon:36655
LOTUS DOI:10.1128/EC.1.5.823-829.2002
Penicillium cyclopium
NCBITaxon:60167
CHEBI 10.1016/S0040-4039(02)01493-4
Penicillium cyclopium
NCBITaxon:60167
LOTUS DOI:10.1016/S0040-4039(02)01493-4
Penicillium cyclopium
NCBITaxon:60167
LOTUS DOI:10.1128/EC.1.5.823-829.2002

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002320 Penicillium rubens Wisconsin 54-1255
NCBITaxon:500485
CLUSTER_DEMONSTRATED genbank:AM920435.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002320MIBIG3
CHEBI:189095CHEBI3-star

This page is generated from data/natural_products/terpenoids/conidiogenone.yaml, which is generated from the committed inventories. Neither is edited by hand.