NaturalProductMech

cucurbitacin C

naturalproductmech:mibig-7bc5e7b427 MINTED SEEDED

Structure

Standard InChIKeyDGIGXLXLGBAJJN-TUOUHCSQSA-N
SMILESCC(=O)OC(C)(C)/C=C/C(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3CC[C@@H](C4(C)C)O)CO)C)C)O)O
Stereochemistryfully defined
Cross-referencespubchem:5281317

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Cucumis sativus
NCBITaxon:3659
SOURCE_ASSERTION mibig:BGC0001315 DOI:10.1038/nplants.2016.183

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Cucurbita foetidissima
NCBITaxon:184136
LOTUS DOI:10.1016/0031-9422(88)84112-8
Bryonia alba
NCBITaxon:243967
LOTUS DOI:10.1016/0031-9422(75)85356-8
Cucumis sativus
NCBITaxon:3659
LOTUS DOI:10.1016/0031-9422(83)85020-1
Cucumis sativus
NCBITaxon:3659
LOTUS DOI:10.1021/JF00103A051

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001315 Cucumis sativus
NCBITaxon:3659
CLUSTER_UNSTATED genbank:MIBIG.BGC0001315.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001315MIBIG3

This page is generated from data/natural_products/terpenoids/cucurbitacin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.