cucurbitacin C
naturalproductmech:mibig-7bc5e7b427 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | DGIGXLXLGBAJJN-TUOUHCSQSA-N |
|---|---|
| SMILES | CC(=O)OC(C)(C)/C=C/C(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3CC[C@@H](C4(C)C)O)CO)C)C)O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:5281317 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Cucumis sativus NCBITaxon:3659 |
SOURCE_ASSERTION | mibig:BGC0001315 | DOI:10.1038/nplants.2016.183 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Cucurbita foetidissima NCBITaxon:184136 |
LOTUS | DOI:10.1016/0031-9422(88)84112-8 |
| Bryonia alba NCBITaxon:243967 |
LOTUS | DOI:10.1016/0031-9422(75)85356-8 |
| Cucumis sativus NCBITaxon:3659 |
LOTUS | DOI:10.1016/0031-9422(83)85020-1 |
| Cucumis sativus NCBITaxon:3659 |
LOTUS | DOI:10.1021/JF00103A051 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001315 | Cucumis sativus NCBITaxon:3659 |
CLUSTER_UNSTATED | genbank:MIBIG.BGC0001315.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001315 | MIBIG | 3 |
This page is generated from data/natural_products/terpenoids/cucurbitacin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.