NaturalProductMech

cyclooctatin

naturalproductmech:mibig-3835812e03 MINTED SEEDED

Structure

Standard InChIKeyMSKFOQCDNOFJAT-SOFYXZRVSA-N
SMILESCC(C)C\1CCC2(/C1=C\CC(C3C(CC(C3C2)CO)O)(C)O)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:5467942

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces melanosporofaciens
NCBITaxon:67327
BGC_CHARACTERIZED mibig:BGC0000677 PMID:19635410

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1007/S00253-013-5440-6
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1016/S1875-5364(17)30018-3
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1021/ACS.JNATPROD.6B00676
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1186/1471-2164-15-97
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.7164/ANTIBIOTICS.45.1587

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000677 Streptomyces melanosporofaciens
NCBITaxon:67327
CLUSTER_DEMONSTRATED genbank:AB448947.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000677MIBIG5

This page is generated from data/natural_products/terpenoids/cyclooctatin.yaml, which is generated from the committed inventories. Neither is edited by hand.