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eutypinic acid

naturalproductmech:mibig-a75acad16f MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyHFSFSKBQIGXUEY-UHFFFAOYSA-N
SMILESCC(=C)C#CC1=C(C=CC(=C1)C(=O)O)O
Stereochemistryfully defined
Cross-referencespubchem:14394291

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Biscogniauxia sp.
NCBITaxon:1896107
SOURCE_ASSERTION mibig:BGC0002290 PMID:32364293

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Curvularia fallax
NCBITaxon:215128
LOTUS DOI:10.1016/0031-9422(90)85203-R
Aspergillus
NCBITaxon:5052
LOTUS DOI:10.1021/NP500324B
Eutypa lata
NCBITaxon:97096
LOTUS DOI:10.1002/HLCA.19890720508

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002290 Biscogniauxia sp.
NCBITaxon:1896107
CLUSTER_DEMONSTRATED genbank:MT109335.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (0 causal) 3 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT eutypinic acid naturalproductmech:mibig-a75acad16f Terpenoids TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

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Provenance

Source conceptSourceVersion
BGC0002290MIBIG2

This page is generated from data/natural_products/terpenoids/eutypinic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.