lycosantalonol

naturalproductmech:mibig-7163f2db37 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKey	QSUSRIKETCUEAR-RHAKXUACSA-N
SMILES	CC(=CCCC(C)(C(=O)CC[C@@]1(C2CC3C1(C3C2)C)C)O)C
Stereochemistry	undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-references	pubchem:101900499

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Solanum lycopersicum NCBITaxon:4081	SOURCE_ASSERTION	mibig:BGC0001322	DOI:10.1371/journal.pone.0119302

Occurrences 0

None cited.

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0001322	Solanum lycopersicum NCBITaxon:4081	CLUSTER_UNSTATED	genbank:KC807995.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Causal graph — biosynthesis 11 nodes, 10 edges

CPT2 evidence from a recombinant precursor-condensation assay and an engineered tomato comparison, kept distinct from native sequence identity and wild-type occurrence. K7WQ45 is a deliberate current native example, not an exact assay-stock assignment. No TPS21/CYP71BN1 reaction, physical complex, exact final-product stereochemistry or producer-grade upgrade is asserted. SEEDED status and source-owned classifications remain unchanged; this is not full-record sign-off.

Subject	Predicate	Object	Notes	Evidence
Current tomato CPT2 native sequence example	is_native_sequence_example_for	Study recombinant CPT2 preparation lacking the first 51 residues	The full native reference is not the truncated, affinity-purified preparation. Spliced CDS translations from JX943884.1/AFW98426.1 and KC807995.1/AGK82801.1 independently equal the 314-residue UniProt sequence. Nucleotide source qualifiers establish species but not cultivar. The study describes deletion of residues1-51, not UniProt's predicted transit-peptide boundary1-61; exact insert, tag and experimental stock sequence remain unverified.	https://www.uniprot.org/uniprotkb/K7WQ45 https://www.ncbi.nlm.nih.gov/nuccore/JX943884.1 https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 DOI:10.1371/journal.pone.0119302 reference https://www.uniprot.org/uniprotkb/K7WQ45 evidence type DATABASE_ASSERTION notes K7WQ45, reviewed entry51/sequence1, 314 residues; annotation2026-09-02. Species Solanum lycopersicum, taxon4081. Current reference, not the complete historical experimental construct or MP1 allele. retrieved on 2026-10-06 reference https://www.ncbi.nlm.nih.gov/nuccore/JX943884.1 evidence type CURATOR_INFERENCE notes Complete spliced-CDS/table1 translation equals GenPept and UniProt; reference equivalence does not establish historical preparation identity. retrieved on 2026-10-06 reference https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 evidence type DATABASE_ASSERTION notes Independent genomic CPT2 reference encodes AGK82801.1; complete CDS within a partial genomic locus. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page5; deliberately selected gene-matched example only. retrieved on 2026-10-06
Study recombinant CPT2 preparation lacking the first 51 residues	was_tested_as_catalyst_in	Recombinant CPT2 radiolabeled substrate-condensation assay	The recombinant protein was produced in E. coli and purified by nickel affinity. This is an in-vitro substrate-condensation experiment, not direct synthesis of lycosantalonol by CPT2 or a native plant multi-enzyme complex.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page5; results page9 and Table2 page10. retrieved on 2026-10-06
Assayed isopentenyl diphosphate	was_substrate_in	Recombinant CPT2 radiolabeled substrate-condensation assay	Radiolabeled IPP was used with zzFPP for the reported kinetic assessment. No binding constant, native cellular rate or exact-isomer yield is inferred.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page5; results page9 and Table2 page10. retrieved on 2026-10-06
Assayed Z,Z-farnesyl diphosphate	was_cosubstrate_in	Recombinant CPT2 radiolabeled substrate-condensation assay	The tested acceptor is Z,Z-farnesyl diphosphate, not E,E-farnesyl diphosphate. This supports the last condensation attributed to NNPP synthesis, not all earlier substrate preferences described from previous studies.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page5; results page9 and Table2 page10. retrieved on 2026-10-06
Recombinant CPT2 radiolabeled substrate-condensation assay	supported_source_assigned_formation_of	Source-assigned nerylneryl diphosphate product	The authors assign the zzFPP-plus-IPP step to NNPP formation. The reported readout hydrolyzes diphosphate groups and counts extracted radiolabel; this kinetic assay alone is not independent structural or stereochemical proof. No direct CPT2-to-lycosantalonol catalytic edge is asserted.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page5; results page9 and Table2 page10. retrieved on 2026-10-06
Current tomato CPT2 native sequence example	is_gene_product_example_for	CPT2 gene in the study 35S overexpression construct	The selected full-length native protein exemplifies the named CPT2 gene product. It is not an identifier for the gene construct, promoter, insertion site or cultivar-specific allele. Transgenic plants are explicitly MP1 in the study; that does not establish a cultivar for the native sequence deposit.	https://www.uniprot.org/uniprotkb/K7WQ45 DOI:10.1371/journal.pone.0119302 reference https://www.uniprot.org/uniprotkb/K7WQ45 evidence type DATABASE_ASSERTION notes K7WQ45, reviewed entry51/sequence1, 314 residues; annotation2026-09-02. Species Solanum lycopersicum, taxon4081. Current reference, not the complete historical experimental construct or MP1 allele. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Transgenic-plant methods page4. retrieved on 2026-10-06
CPT2 gene in the study 35S overexpression construct	was_used_for_overexpression_in	Selected CPT2-overexpressing tomato plants	The study uses first-generation 35S-CPT2 transgenic tomato plants. Three plants selected for high leaflet lycosantalene were examined by petiolule GC-MS; they are selected individuals, not an unbiased yield estimate for all lines or evidence that all plants accumulate the product.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods page4; results pages8-9 and Figure4B-D. retrieved on 2026-10-06 snippet three individual transgenic tomato lines
Selected CPT2-overexpressing tomato plants	was_profiled_in	Petiolule-extract GC-MS comparison	Hexane extracts of whole petiolules from all three selected plants had source-assigned lycosantalonol peaks. Figure4 displays selected-ion traces and a standard comparison. In S2, peak4 from chromatogramD has a dominant m/z69 signal rather than the dominant m/z109 in B, C and standardE; the cause of that relative-pattern difference is unresolved. The source's three-plant assignment is retained, not independently confirmed for each plant or used as exact stereochemical proof. The tissue-ratio experiment in Table1 measured lycosantalene, not lycosantalonol.	DOI:10.1371/journal.pone.0119302 DOI:10.1371/journal.pone.0119302.s002 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Methods pages4-5; results pages8-9 and Figure4B-E. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302.s002 evidence type CURATOR_INFERENCE notes Complete official supplementary TIFF and enlarged peak4 panels visually inspected. Relative spectral-pattern discrepancy not assigned to contamination, coelution, annotation error or another cause. retrieved on 2026-10-06
Non-transformed tomato comparator	was_profiled_in	Petiolule-extract GC-MS comparison	The study did not detect lycosantalonol in non-transformed samples with the reported methods. This is bounded non-detection, not a demonstrated absence of natural synthesis or of undetected downstream derivatives.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Results pages8-9, Figure4A and discussion pages10-11. retrieved on 2026-10-06
Petiolule-extract GC-MS comparison	supports_cpt2_associated_detection_of	Source-assigned lycosantalonol in transgenic petiolules	CPT2 overexpression is associated with detection of source-assigned lycosantalonol in the engineered context. This does not establish CPT2 as its direct final-step catalyst, a unique rate-limiting step, an exact stereochemical assignment to this owner, or native wild-type production. TPS21 and CYP71BN1 chemistry is described partly from earlier work whose full evidence was not inspected; those reactions are not added here.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained full main paper, main figures, tables and S2 mass-spectrum figure inspected; other SI assets unread. Results pages8-9, Figure4 and discussion pages10-11. retrieved on 2026-10-06

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Causal graph — biosynthesis 10 nodes, 12 edges

Transcript-level context for CPT2, TPS21 and CYP71BN1 in the lycosantalonol study, with native protein examples explicitly distinct from gene assays and historical alleles. Adds TPS21 and CYP71BN1 reference examples without asserting their reaction chemistry from incompletely inspected earlier work. Tissue-level RNA distributions are not protein abundance, single-cell localization, direct regulation or a physical complex. No source-grade, origin, stereochemistry or SEEDED-status upgrade; not full-record sign-off.

Subject	Predicate	Object	Notes	Evidence
Current tomato CPT2 native protein example	is_gene_product_example_for	Study CPT2 gene assayed by transcript measurement	Deliberately selected species-matched native example, not the historical tissue allele. Complete spliced CDS translation equals AGK82801.1 and the 314-residue UniProt sequence. The S1 qRT-PCR primer pair has one correctly oriented exact match at spliced-CDS positions54..261, 1-based inclusive, among the11 annotated CDSs of KC807995.1. This bounded match is not genome-wide primer specificity, full experimental transcript sequencing or a measurement of protein abundance.	https://www.uniprot.org/uniprotkb/K7WQ45 https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 DOI:10.1371/journal.pone.0119302.s006 DOI:10.1371/journal.pone.0119302 reference https://www.uniprot.org/uniprotkb/K7WQ45 evidence type DATABASE_ASSERTION notes Solanum lycopersicum taxon4081; reviewed entry51/sequence1, 314 residues; last annotation2026-09-02. Native reference only. retrieved on 2026-10-06 reference https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 evidence type CURATOR_INFERENCE notes Complete spliced-CDS/table1 translation independently equals GenPept and UniProt; genomic source qualifiers establish species but not cultivar. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302.s006 evidence type CURATOR_INFERENCE notes Official one-page S1 table visually read; forward/reverse primer rows checked verbatim and compared with spliced reference CDSs. No assay-stock identity inferred. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Gene-named qRT-PCR methods page4 and results pages6-7. retrieved on 2026-10-06
Current tomato TPS21 native protein example	is_gene_product_example_for	Study TPS21 gene assayed by transcript measurement	Deliberately selected species-matched native example, not the historical tissue allele. Complete spliced CDS translation equals AGK82800.1 and the 792-residue UniProt sequence. The S1 qRT-PCR primer pair has one correctly oriented exact match at spliced-CDS positions1454..1560, 1-based inclusive, among the11 annotated CDSs of KC807995.1. This bounded match is not genome-wide primer specificity, full experimental transcript sequencing or a measurement of protein abundance.	https://www.uniprot.org/uniprotkb/R9R6P6 https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 DOI:10.1371/journal.pone.0119302.s006 DOI:10.1371/journal.pone.0119302 reference https://www.uniprot.org/uniprotkb/R9R6P6 evidence type DATABASE_ASSERTION notes Solanum lycopersicum taxon4081; unreviewed entry53/sequence1, 792 residues; last annotation2026-06-10. Native reference only. retrieved on 2026-10-06 reference https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 evidence type CURATOR_INFERENCE notes Complete spliced-CDS/table1 translation independently equals GenPept and UniProt; genomic source qualifiers establish species but not cultivar. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302.s006 evidence type CURATOR_INFERENCE notes Official one-page S1 table visually read; forward/reverse primer rows checked verbatim and compared with spliced reference CDSs. No assay-stock identity inferred. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Gene-named qRT-PCR methods page4 and results pages6-7. retrieved on 2026-10-06
Current tomato CYP71BN1 native protein example	is_gene_product_example_for	Study CYP71BN1 gene assayed by transcript measurement	Deliberately selected species-matched native example, not the historical tissue allele. Complete spliced CDS translation equals AGK82807.1 and the 506-residue UniProt sequence. The S1 qRT-PCR primer pair has one correctly oriented exact match at spliced-CDS positions752..909, 1-based inclusive, among the11 annotated CDSs of KC807995.1. This bounded match is not genome-wide primer specificity, full experimental transcript sequencing or a measurement of protein abundance. K4CI56 is an unreviewed reference with Heinz1706 source metadata and generic Cytochrome P450-1/LOC101251011 annotation; exact CDS and primer correspondence, not the generic name, supports the CYP71BN1 example. No MP1 stock assignment.	https://www.uniprot.org/uniprotkb/K4CI56 https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 DOI:10.1371/journal.pone.0119302.s006 DOI:10.1371/journal.pone.0119302 reference https://www.uniprot.org/uniprotkb/K4CI56 evidence type DATABASE_ASSERTION notes Solanum lycopersicum taxon4081; unreviewed entry71/sequence1, 506 residues; last annotation2026-09-02. Native reference only. retrieved on 2026-10-06 reference https://www.ncbi.nlm.nih.gov/nuccore/KC807995.1 evidence type CURATOR_INFERENCE notes Complete spliced-CDS/table1 translation independently equals GenPept and UniProt; genomic source qualifiers establish species but not cultivar. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302.s006 evidence type CURATOR_INFERENCE notes Official one-page S1 table visually read; forward/reverse primer rows checked verbatim and compared with spliced reference CDSs. No assay-stock identity inferred. retrieved on 2026-10-06 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Gene-named qRT-PCR methods page4 and results pages6-7. retrieved on 2026-10-06
Study CPT2 gene assayed by transcript measurement	had_transcripts_measured_in	Study tissue and developmental-stage qRT-PCR comparison	qRT-PCR measured RNA across the study's tissue and developmental-stage panel. Methods describe EF-1a normalization and a standard-curve approach for cross-gene comparison; Figure2 has three biological replicates and three technical replicates. This does not identify a historical full-length allele or measure the corresponding protein, catalytic flux or cell-specific localization.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Methods page4; results page6 and Figure2. retrieved on 2026-10-06
Study CPT2 gene assayed by transcript measurement	had_transcripts_measured_in	Study whole-petiolule and trichome-fraction qRT-PCR comparison	RNA was compared between whole petiolules, trichome-depleted petiolules and isolated trichomes. Figure3 has four biological replicates with three technical replicates each. These tissue fractions are not single-cell measurements, proof of fraction purity or direct evidence of a protein's location.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Fraction preparation pages3-4; results pages6-7 and Figure3. retrieved on 2026-10-06
Study TPS21 gene assayed by transcript measurement	had_transcripts_measured_in	Study tissue and developmental-stage qRT-PCR comparison	qRT-PCR measured RNA across the study's tissue and developmental-stage panel. Methods describe EF-1a normalization and a standard-curve approach for cross-gene comparison; Figure2 has three biological replicates and three technical replicates. This does not identify a historical full-length allele or measure the corresponding protein, catalytic flux or cell-specific localization.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Methods page4; results page6 and Figure2. retrieved on 2026-10-06
Study TPS21 gene assayed by transcript measurement	had_transcripts_measured_in	Study whole-petiolule and trichome-fraction qRT-PCR comparison	RNA was compared between whole petiolules, trichome-depleted petiolules and isolated trichomes. Figure3 has four biological replicates with three technical replicates each. These tissue fractions are not single-cell measurements, proof of fraction purity or direct evidence of a protein's location.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Fraction preparation pages3-4; results pages6-7 and Figure3. retrieved on 2026-10-06
Study CYP71BN1 gene assayed by transcript measurement	had_transcripts_measured_in	Study tissue and developmental-stage qRT-PCR comparison	qRT-PCR measured RNA across the study's tissue and developmental-stage panel. Methods describe EF-1a normalization and a standard-curve approach for cross-gene comparison; Figure2 has three biological replicates and three technical replicates. This does not identify a historical full-length allele or measure the corresponding protein, catalytic flux or cell-specific localization.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Methods page4; results page6 and Figure2. retrieved on 2026-10-06
Study CYP71BN1 gene assayed by transcript measurement	had_transcripts_measured_in	Study whole-petiolule and trichome-fraction qRT-PCR comparison	RNA was compared between whole petiolules, trichome-depleted petiolules and isolated trichomes. Figure3 has four biological replicates with three technical replicates each. These tissue fractions are not single-cell measurements, proof of fraction purity or direct evidence of a protein's location.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Fraction preparation pages3-4; results pages6-7 and Figure3. retrieved on 2026-10-06
Study tissue and developmental-stage qRT-PCR comparison	supports_reported_transcript_pattern	Reported overlapping petiolule transcript distributions	The authors report the highest transcript levels for all three genes in young petiolules within the examined panel. TPS21 is broadly expressed across several tissues, unlike the more pronounced CPT2/CYP71BN1 petiolule pattern. Figure2 error bars overlap for some comparisons; no new significance test or exclusive tissue expression is asserted.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Results page6 and Figure2; source interpretation, not re-estimated bar values. retrieved on 2026-10-06
Study whole-petiolule and trichome-fraction qRT-PCR comparison	supports_reported_transcript_pattern	Reported overlapping petiolule transcript distributions	Normalized transcript levels are higher in trichome-depleted petiolules than in whole petiolules and lower in isolated trichomes. This supports the source's predominantly non-trichome transcript interpretation, not an absence from every trichome cell, protein localization, or evidence that one of the three genes regulates another.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type PRIMARY_EXPERIMENT notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Results pages6-7 and Figure3. retrieved on 2026-10-06 snippet mostly in non-trichome cells
Reported overlapping petiolule transcript distributions	provides_correlative_expression_context_for	Source-discussed lycosantalonol biosynthesis context	The transcript distributions provide context for the lycosantalonol pathway discussed in this paper. They do not establish direct TPS21/CYP71BN1 reactions, coordinated protein abundance, a physical complex, wild-type product detection, unique rate limitation or the owner's exact stereochemistry. This graph does not borrow reaction claims from earlier papers whose full evidence remains uninspected. The separate CPT2 intervention graph retains the engineered-product comparison; no cross-graph node edge is asserted.	DOI:10.1371/journal.pone.0119302 reference DOI:10.1371/journal.pone.0119302 evidence type CURATOR_INFERENCE notes Retained complete main paper and Figures2-3 visually inspected; S1 primer table and S2 figure inspected, other supplementary assets unread. Results pages6-11 and discussion pages11-13. retrieved on 2026-10-06

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Explore across X-Mech

AntibioticMech (lycosantalonol) ↗ MediaIngredientMech (naturalproductmech:mibig-7163f2db37) ↗ TaxonMech: Solanum lycopersicum (NCBITaxon:4081) ↗ PathwayMech (mibig:BGC0001322) ↗

Provenance

Source concept	Source	Version
BGC0001322	MIBIG	3

This page is generated from data/natural_products/terpenoids/lycosantalonol.yaml, which is generated from the committed inventories. Neither is edited by hand.