mangicol A
CHEBI:156320 EXACT SEEDED
A sesterterpenoid natural product found in the fungus Fusarium heterosporum. It exhibits significant antiinflammatory activity in the PMA-induced mouse ear edema model.
Structure
| Standard InChIKey | KJHICOOTWQEHPN-DVMFOLSNSA-N |
|---|---|
| SMILES | [H][C@@]12CC[C@H](C)[C@@]11[C@H](O)C[C@H](C)C1=C[C@@]1(C)CC[C@](C)(C[C@H](O)[C@H](O)[C@@](C)(O)CO)[C@@]21[H] |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA016972 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fusarium equiseti NCBITaxon:61235 |
SOURCE_ASSERTION | mibig:BGC0001659 | DOI:10.1055/s-0035-1556229 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Fusarium heterosporum NCBITaxon:42747 |
LOTUS | DOI:10.1021/JO000081H |
| Fusarium heterosporum NCBITaxon:42747 |
CHEBI | PMID:10956462 |
| Fusarium equiseti NCBITaxon:61235 |
CHEBI | 10.1055/s-0035-1556229 |
| Fusarium equiseti NCBITaxon:61235 |
LOTUS | DOI:10.1055/S-0035-1556229 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001659 | Fusarium equiseti NCBITaxon:61235 |
CLUSTER_UNSTATED | genbank:KU376508.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001659 | MIBIG | 3 |
| CHEBI:156320 | CHEBI | 3-star |
This page is generated from data/natural_products/terpenoids/mangicol-a.yaml, which is generated from the committed inventories. Neither is edited by hand.