NaturalProductMech

methylenomycin A

naturalproductmech:mibig-697eb70f76 MINTED SEEDED

Structure

Standard InChIKeyHBECYYFDLZZMPL-WLGLDCGKSA-N
SMILESC[C@@]12O[C@]1(C)C(=O)C(=C)[C@H]2C(O)=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA013552

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces coelicolor A3(2)
NCBITaxon:100226
SOURCE_ASSERTION mibig:BGC0000914 PMID:19054329

Occurrences 24

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S10295-013-1383-2
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1016/0378-1119(91)90352-C
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1016/0378-1119(92)90537-Y
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1039/B101615F
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1073/PNAS.0805530105
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1099/00221287-95-1-96
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1111/J.1365-2958.2008.06560.X
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1128/JB.00017-11
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1128/JB.173.4.1523-1529.1991
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1128/JB.179.17.5511-5515.1997
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1186/S13036-017-0071-6
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S10295-013-1383-2
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1016/0378-1119(91)90352-C
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1016/0378-1119(92)90537-Y
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1039/B101615F
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1073/PNAS.0805530105
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1099/00221287-95-1-96
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1111/J.1365-2958.2008.06560.X
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1128/JB.00017-11
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1128/JB.173.4.1523-1529.1991
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1128/JB.179.17.5511-5515.1997
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1186/S13036-017-0071-6
Streptomyces violaceoruber
NCBITaxon:1935
LOTUS DOI:10.1111/J.1574-6968.2002.TB11290.X
Streptomyces violaceoruber
NCBITaxon:1935
LOTUS DOI:10.7164/ANTIBIOTICS.27.393

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000914 Streptomyces coelicolor A3(2)
NCBITaxon:100226
CLUSTER_UNSTATED genbank:AL589148.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000914MIBIG5

This page is generated from data/natural_products/terpenoids/methylenomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.