(+)-Τ-muurolol
CHEBI:63704 EXACT SEEDED
A cadinane sesquiterpenoid that consists of 4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene having a hydroxy substituent at position 1 and (1R,4R,4aS,8aR)-configuration.
Structure
| Standard InChIKey | LHYHMMRYTDARSZ-KBUPBQIOSA-N |
|---|---|
| SMILES | CC1=C[C@@H]2[C@H](CC[C@@]([C@@H]2CC1)(C)O)C(C)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:51394521 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
SOURCE_ASSERTION | mibig:BGC0000675 | PMID:21276937 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Scapania undulata NCBITaxon:215256 |
LOTUS | DOI:10.1016/S0031-9422(00)00220-X |
| Scapania undulata NCBITaxon:215256 |
LOTUS | DOI:10.1016/S0031-9422(00)90406-0 |
| Scapania undulata NCBITaxon:215256 |
LOTUS | DOI:10.1080/10412905.1996.9700572 |
| Streptomyces clavuligerus NCBITaxon:1901 |
LOTUS | DOI:10.1016/J.CHEMBIOL.2010.11.008 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000675 | Streptomyces clavuligerus ATCC 27064 NCBITaxon:1901 |
CLUSTER_UNSTATED | genbank:DS570654.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000675 | MIBIG | 5 |
| CHEBI:63704 | CHEBI | 3-star |
This page is generated from data/natural_products/terpenoids/muurolol.yaml, which is generated from the committed inventories. Neither is edited by hand.