NaturalProductMech

napyradiomycin

naturalproductmech:mibig-fe51add3cd MINTED SEEDED

Structure

Standard InChIKeyBCPWMPCOEAOEDD-NQSCOFRMSA-N
SMILESCC(=CCC/C(=C/C[C@]12C(=O)C3=CC(=CC(=C3C(=O)[C@]1(C[C@H](C(O2)(C)C)Cl)Cl)O)O)/C)C
Stereochemistryfully defined
Cross-referencespubchem:6438953

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. CNQ525
NCBITaxon:418855
SOURCE_ASSERTION mibig:BGC0000652 DOI:10.1021/np058011z

Occurrences 15

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.7164/ANTIBIOTICS.46.1890
Streptomyces aureus
NCBITaxon:193461
LOTUS DOI:10.1021/ACS.JNATPROD.7B00211
Streptomyces aureus
NCBITaxon:193461
LOTUS DOI:10.1111/1462-2920.14529
Streptomyces aureus
NCBITaxon:193461
LOTUS DOI:10.3390/MD11062113
Streptomyces aureus
NCBITaxon:193461
LOTUS DOI:10.3390/MD14100188
Streptomyces aculeolatus
NCBITaxon:270689
LOTUS DOI:10.1021/ACS.JNATPROD.7B00211
Streptomyces aculeolatus
NCBITaxon:270689
LOTUS DOI:10.1111/1462-2920.14529
Streptomyces aculeolatus
NCBITaxon:270689
LOTUS DOI:10.3390/MD11062113
Streptomyces aculeolatus
NCBITaxon:270689
LOTUS DOI:10.3390/MD14100188
Streptomyces antimycoticus
NCBITaxon:68175
LOTUS DOI:10.1021/ACS.JNATPROD.7B00211
Streptomyces antimycoticus
NCBITaxon:68175
LOTUS DOI:10.1111/1462-2920.14529
Streptomyces antimycoticus
NCBITaxon:68175
LOTUS DOI:10.3390/MD11062113
Streptomyces antimycoticus
NCBITaxon:68175
LOTUS DOI:10.3390/MD14100188
Streptomyces ruber
NCBITaxon:83378
LOTUS DOI:10.7164/ANTIBIOTICS.39.487
Streptomyces ruber
NCBITaxon:83378
LOTUS DOI:10.7164/ANTIBIOTICS.39.494

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000652 Streptomyces sp. CNQ525
NCBITaxon:418855
CLUSTER_UNSTATED genbank:EF397639.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000652MIBIG5

This page is generated from data/natural_products/terpenoids/napyradiomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.