NaturalProductMech

nivalenol

naturalproductmech:mibig-dcf873f38b MINTED SEEDED toxin

Structure

Standard InChIKeyUKOTXHQERFPCBU-XBXCNEFVSA-N
SMILESCC1=C[C@H]2O[C@@H]3[C@H](O)[C@@H](O)[C@](C)([C@@]2(CO)[C@H](O)C1=O)[C@]31CO1
Stereochemistryfully defined
Cross-referenceschembl:CHEMBL509655, pubchem:5284433

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fusarium graminearum
NCBITaxon:5518
SOURCE_ASSERTION mibig:BGC0000930 DOI:10.1128/aem.68.5.2148-2154.2002

Occurrences 7

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fusarium culmorum
NCBITaxon:5516
LOTUS DOI:10.1128/AEM.56.10.3047-3051.1990
Fusarium crookwellense
NCBITaxon:56641
LOTUS DOI:10.1128/AEM.54.8.2147-2148.1988
Fusarium tricinctum
NCBITaxon:61284
LOTUS DOI:10.1128/AEM.48.4.857-858.1984
Fusarium graminearum
NCBITaxon:5518
LOTUS DOI:10.1007/BF00596678
Fusarium graminearum
NCBITaxon:5518
LOTUS DOI:10.1007/BF00629768
Fusarium graminearum
NCBITaxon:5518
LOTUS DOI:10.1080/00275514.1988.12025747
Fusarium graminearum
NCBITaxon:5518
LOTUS DOI:10.2307/3807578

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000930 Fusarium graminearum
NCBITaxon:5518
CLUSTER_UNSTATED genbank:AF336365.2

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Bioactivities 1

AssayResultReference
CCRIS mutagenicity studiesACTIVEpubchem.aid:1259407

Provenance

Source conceptSourceVersion
BGC0000930MIBIG4

This page is generated from data/natural_products/terpenoids/nivalenol.yaml, which is generated from the committed inventories. Neither is edited by hand.