platencin
naturalproductmech:mibig-560750e959 MINTED SEEDED
Structure
| Standard InChIKey | DWUHGPPFFABTIY-KMVHLTCXSA-N |
|---|---|
| SMILES | C[C@@]1(C2C[C@@H]3CC[C@]2(CC3=C)C=CC1=O)CCC(=O)NC4=C(C=CC(=C4O)C(=O)O)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:44450228 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces platensis NCBITaxon:58346 |
BGC_CHARACTERIZED | mibig:BGC0001156 | PMID:20232845 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces platensis NCBITaxon:58346 |
LOTUS | DOI:10.1021/OL100342M |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001156 | Streptomyces platensis NCBITaxon:58346 |
CLUSTER_DEMONSTRATED | genbank:GQ398492.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 2
| Assay | Result | Reference |
|---|---|---|
| Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | ACTIVE | PMID:33229545 |
| qHTS for activators of Nrf2/ARE signaling pathway screened against the NCATS CANVASS Library | ACTIVE | PMID:30648156 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001156 | MIBIG | 5 |
This page is generated from data/natural_products/terpenoids/platencin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.