NaturalProductMech

pleuromutilin

naturalproductmech:mibig-9195c6539c MINTED SEEDED

Structure

Standard InChIKeyZRZNJUXESFHSIO-HXDNZQJBSA-N
SMILESC=C[C@]1(C)C[C@@H](OC(=O)CO)[C@]2(C)[C@@H](C)CC[C@]3(CCC(=O)[C@H]32)[C@@H](C)[C@@H]1O
Stereochemistryfully defined
Cross-referencespubchem:46782767, npatlas:NPA033323

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Rhodocybe pseudopiperita
NCBITaxon:693819
SOURCE_ASSERTION mibig:BGC0002181 DOI:10.2174/2211352519666211130111723

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Omphalina mutila
NCBITaxon:648683
LOTUS DOI:10.1016/S0040-4020(01)90949-4

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002181 Rhodocybe pseudopiperita
NCBITaxon:693819
CLUSTER_UNSTATED genbank:LC314149.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002181MIBIG3

This page is generated from data/natural_products/terpenoids/pleuromutilin.yaml, which is generated from the committed inventories. Neither is edited by hand.