PR-toxin
naturalproductmech:mibig-3ddeaf475e MINTED SEEDED toxin
Structure
| Standard InChIKey | GSPFUBNBRPVALJ-UHFFFAOYSA-N |
|---|---|
| SMILES | CC1C(C2C(O2)C3=CC(=O)C4(CC13C)C(O4)(C)C=O)OC(=O)C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:440907, npatlas:NPA009783 |
Filing pathway
Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium roqueforti FM164 NCBITaxon:1365484 |
SOURCE_ASSERTION | mibig:BGC0000667 | DOI:10.1016/0040-4020(75)85003-4 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Penicillium roqueforti NCBITaxon:5082 |
LOTUS | DOI:10.1016/0040-4020(80)88024-0 |
| Penicillium roqueforti NCBITaxon:5082 |
LOTUS | DOI:10.1016/J.FGB.2013.10.009 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000667 | Penicillium roqueforti FM164 NCBITaxon:1365484 |
CLUSTER_UNSTATED | genbank:HG792016.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 2
| Assay | Result | Reference |
|---|---|---|
| CCRIS mutagenicity studies | ACTIVE | pubchem.aid:1259407 |
| GENE-TOX mutagenicity studies | ACTIVE | pubchem.aid:1259408 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000667 | MIBIG | 3 |
This page is generated from data/natural_products/terpenoids/pr-toxin.yaml, which is generated from the committed inventories. Neither is edited by hand.