NaturalProductMech

(R)-nephthenol

CHEBI:82799 EXACT SEEDED

A cembrane diterpenoid obtained by regio- and stereoselective hydration of the exocyclic double bond of cembrene C.

Structure

Standard InChIKeyZJWQYSDAWSDJRA-QPHFJTKNSA-N
SMILESC/C/1=C\CC/C(=C/C[C@@H](CC/C(=C/CC1)/C)C(C)(C)O)/C
Stereochemistryfully defined
Cross-referencespubchem:6443020

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Stereum hirsutum FP-91666 SS1
NCBITaxon:721885
SOURCE_ASSERTION mibig:BGC0002219 PMID:30905831

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Sarcophyton trocheliophorum
NCBITaxon:205097
LOTUS DOI:10.1021/JO00334A036
Litophyton arboreum
NCBITaxon:2969260
LOTUS DOI:10.1002/CBDV.201000016
Sinularia erecta
NCBITaxon:3286376
LOTUS DOI:10.1021/NP9705064
Sinularia ovispiculata
NCBITaxon:3286446
LOTUS DOI:10.1021/NP50101A024
Guarea kunthiana
NCBITaxon:485821
LOTUS DOI:10.1590/S0103-50532004000500025
Sarcophyton glaucum
NCBITaxon:70919
LOTUS DOI:10.1248/CPB.37.631

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002219 Stereum hirsutum FP-91666 SS1
NCBITaxon:721885
CLUSTER_DEMONSTRATED genbank:JH687388.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002219MIBIG2
CHEBI:82799CHEBI3-star

This page is generated from data/natural_products/terpenoids/r-nephthenol.yaml, which is generated from the committed inventories. Neither is edited by hand.