NaturalProductMech

tirucalla-7,24-dien-3β-ol

CHEBI:63468 EXACT SEEDED

A tirucallane triterpenoid that is tirucalla-7,24-diene substituted by a β-hydroxy group at position 3.

Structure

Standard InChIKeyDICCPNLDOZNSML-CEEMYSEHSA-N
SMILESC[C@@H](CCC=C(C)C)[C@@H]1CC[C@]2([C@]1(CC[C@H]3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
Stereochemistryfully defined
Cross-referencespubchem:12302184

Filing pathway

Terpenoids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Arabidopsis thaliana
NCBITaxon:3702
SOURCE_ASSERTION mibig:BGC0001314 PMID:25502595

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Dysoxylum lenticellatum
NCBITaxon:1679374
LOTUS DOI:10.1021/NP2006296
Dysoxylum lenticellatum
NCBITaxon:1679374
CHEBI PMID:21954912
Euphorbia tithymaloides
NCBITaxon:212310
LOTUS DOI:10.1021/NP070174V
Picris hieracioides
NCBITaxon:212690
LOTUS DOI:10.1248/CPB.43.1634
Ixeris chinensis
NCBITaxon:318058
LOTUS DOI:10.1248/CPB.44.509
Arabidopsis thaliana
NCBITaxon:3702
LOTUS DOI:10.1016/S0040-4039(00)01347-2

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001314 Arabidopsis thaliana
NCBITaxon:3702
CLUSTER_UNSTATED genbank:NC_003076.8

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001314MIBIG3
CHEBI:63468CHEBI3-star

This page is generated from data/natural_products/terpenoids/tirucalla-7-24-dien-3-ol.yaml, which is generated from the committed inventories. Neither is edited by hand.