NaturalProductMech

albonoursin

CHEBI:71609 EXACT SEEDED

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which the two hydrogen at position 3 and those at position 6 are replaced by benzylidene and isobutylidene groups (the 3Z,6Z-geoisomer).

Structure

Standard InChIKeyLCIIOYPBHIZBOD-JMVBYTIWSA-N
SMILESCC(C)\C=C1/NC(=O)\C(NC1=O)=C\C1=CC=CC=C1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA016033, pubchem:6109346

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces noursei ATCC 11455
NCBITaxon:316284
SOURCE_ASSERTION mibig:BGC0000851 PMID:12498889

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Micromonospora
NCBITaxon:1873
LOTUS DOI:10.1021/NP0104572
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1016/S0040-4039(01)90934-7
Streptomyces noursei
NCBITaxon:1971
LOTUS DOI:10.1080/14786419.2015.1045509
Streptomyces noursei
NCBITaxon:1971
LOTUS DOI:10.3390/MD11041035
Streptomyces albulus
NCBITaxon:1971
LOTUS DOI:10.7164/ANTIBIOTICS.52.1017

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000851 Streptomyces noursei ATCC 11455
NCBITaxon:316284
CLUSTER_UNSTATED genbank:AY129235.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000851MIBIG5
CHEBI:71609CHEBI3-star

This page is generated from data/natural_products/unclassified/albonoursin.yaml, which is generated from the committed inventories. Neither is edited by hand.