althiomycin
naturalproductmech:mibig-a83e5a3fde MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | NZGOIHZOTAJJCD-UHFFFAOYSA-N |
|---|---|
| SMILES | COC1=CC(=O)N(C1)C(=O)C2CSC(=N2)C(CO)NC(=O)C3=CSC(=CN=O)N3 |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:5464477 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Myxococcus xanthus NCBITaxon:34 |
BGC_CHARACTERIZED | mibig:BGC0000955 | PMID:21626639 |
| Serratia marcescens subsp. marcescens Db11 NCBITaxon:273526 |
SOURCE_ASSERTION | mibig:BGC0001415 | PMID:23028578 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Myxococcus xanthus NCBITaxon:34 |
LOTUS | DOI:10.1002/CBIC.201100154 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000955 | Myxococcus xanthus NCBITaxon:34 |
CLUSTER_DEMONSTRATED | genbank:FR831800.1 |
| mibig:BGC0001415 | Serratia marcescens subsp. marcescens Db11 NCBITaxon:273526 |
CLUSTER_UNSTATED | genbank:HG326223.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000955, BGC0001415. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000955 | MIBIG | 5 |
| BGC0001415 | MIBIG | 4 |
This page is generated from data/natural_products/unclassified/althiomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.