NaturalProductMech

apratoxin A

naturalproductmech:mibig-1b1273b287 MINTED SEEDED

Structure

Standard InChIKeyKXUJXPZXILTXDA-JHMIWIOGSA-N
SMILESCC[C@H](C)[C@@H]1C(=O)N2CCC[C@H]2C(=O)O[C@@H](C[C@H](C[C@@H]([C@@H](C3=N[C@H](CS3)/C=C(/C(=O)N[C@H](C(=O)N([C@H](C(=O)N1C)C)C)CC4=CC=C(C=C4)OC)\C)C)O)C)C(C)(C)C
Stereochemistryfully defined
Cross-referencesnpatlas:NPA012281

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Moorena bouillonii bAprat14
NCBITaxon:2530358
SOURCE_ASSERTION mibig:BGC0002542 DOI:10.1021/ja010453j

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Lyngbya majuscula
NCBITaxon:158786
LOTUS DOI:10.1021/JA010453J

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002542 Moorena bouillonii bAprat14
NCBITaxon:2530358
CLUSTER_DEMONSTRATED genbank:MG890637.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002542MIBIG2

This page is generated from data/natural_products/unclassified/apratoxin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.