NaturalProductMech

clifednamide A

naturalproductmech:mibig-f121d32032 MINTED SEEDED

Structure

Standard InChIKeyRKXLUXSTSOYJOS-ONSBZXJCSA-N
SMILESC[C@@H]1C[C@@H]2[C@H]3C[C@H]4/C=C/C(=C5C(=O)[C@H](CCCNC(=O)/C=C/C[C@@H]4[C@H]3C=C[C@H]2[C@@H]1C(=O)C)NC5=O)O
Stereochemistryfully defined
Cross-referencespubchem:102048821

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. JV178
NCBITaxon:858632
SOURCE_ASSERTION mibig:BGC0001553 PMID:29249153

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces neyagawaensis
NCBITaxon:42238
LOTUS DOI:10.1021/ACSSYNBIO.7B00349
Streptomyces neyagawaensis
NCBITaxon:42238
LOTUS DOI:10.1128/GENOMEA.01401-17
Streptomyces purpeofuscus
NCBITaxon:67352
LOTUS DOI:10.1021/ACSSYNBIO.7B00349
Streptomyces purpeofuscus
NCBITaxon:67352
LOTUS DOI:10.1128/GENOMEA.01401-17
Streptomyces torulosus
NCBITaxon:68276
LOTUS DOI:10.1021/ACSSYNBIO.7B00349
Streptomyces torulosus
NCBITaxon:68276
LOTUS DOI:10.1128/GENOMEA.01401-17

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001553 Streptomyces sp. JV178
NCBITaxon:858632
CLUSTER_UNSTATED genbank:MF893273.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001553MIBIG5

This page is generated from data/natural_products/unclassified/clifednamide-a-2.yaml, which is generated from the committed inventories. Neither is edited by hand.