corynebactin
CHEBI:31432 EXACT SEEDED
A crown compound that is enterobactin in which the pro-R hydrogens at positions 2, 6 and 10 of the trilactone backbone are replaced by methyl groups, and in which a glycine spacer separates the trilactone backbone from each of the catecholamide arms. It is the endogenous siderophore of Bacillus subtilis, used for the acquisition of iron.
Structure
| Standard InChIKey | RCQTVEFBFUNTGM-BDVHUIKKSA-N |
|---|---|
| SMILES | C[C@@H]1[C@@H](C(=O)O[C@@H]([C@@H](C(=O)O[C@@H]([C@@H](C(=O)O1)NC(=O)CNC(=O)C2=C(C(=CC=C2)O)O)C)NC(=O)CNC(=O)C3=C(C(=CC=C3)O)O)C)NC(=O)CNC(=O)C4=C(C(=CC=C4)O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:125349 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Bacillus velezensis FZB42 NCBITaxon:326423 |
BGC_CHARACTERIZED | mibig:BGC0001185 | PMID:18957859 |
| Bacillus subtilis subsp. subtilis str. 168 NCBITaxon:224308 |
SOURCE_ASSERTION | mibig:BGC0000309 | PMID:9384377 |
Occurrences 5
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Bacillus subtilis NCBITaxon:1423 |
LOTUS | DOI:10.1074/JBC.M009140200 |
| Bacillus subtilis NCBITaxon:1423 |
CHEBI | PMID:11112781 |
| Corynebacterium glutamicum NCBITaxon:1718 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0034591 |
| Corynebacterium glutamicum NCBITaxon:1718 |
LOTUS | DOI:10.1515/ZNC-1997-7-820 |
| Bacillus velezensis NCBITaxon:492670 |
LOTUS | DOI:10.1159/000142891 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001185 | Bacillus velezensis FZB42 NCBITaxon:326423 |
CLUSTER_DEMONSTRATED | genbank:CP000560.1 |
| mibig:BGC0000309 | Bacillus subtilis subsp. subtilis str. 168 NCBITaxon:224308 |
CLUSTER_UNSTATED | genbank:AL009126.3 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 2
name-disagreement — ChEBI calls this structure 'corynebactin' and MIBiG calls it 'bacillibactin'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000309, BGC0001185. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001185 | MIBIG | 5 |
| BGC0000309 | MIBIG | 5 |
| CHEBI:31432 | CHEBI | 3-star |
This page is generated from data/natural_products/unclassified/corynebactin.yaml, which is generated from the committed inventories. Neither is edited by hand.