Cryptophycin A
naturalproductmech:mibig-533ddeefb5 MINTED SEEDED
Structure
| Standard InChIKey | PSNOPSMXOBPNNV-XUMGCJJFSA-N |
|---|---|
| SMILES | C[C@@H]1CNC(=O)[C@@H](NC(=O)/C=C/C[C@H](OC(=O)[C@@H](OC1=O)CC(C)C)[C@H](C)[C@@H]2[C@H](O2)C3=CC=CC=C3)CC4=CC(=C(C=C4)OC)Cl |
| Stereochemistry | fully defined |
| Cross-references | cyanometdb:CyanoMetDB_1104, npatlas:NPA013071 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Nostoc sp. ATCC 53789 NCBITaxon:76335 |
SOURCE_ASSERTION | mibig:BGC0000975 | DOI:10.1021/cb6004307 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nostoc NCBITaxon:1177 |
LOTUS | DOI:10.1021/JA00090A020 |
| Nostoc NCBITaxon:1177 |
LOTUS | DOI:10.1021/JA00154A002 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000975 | Nostoc sp. ATCC 53789 NCBITaxon:76335 |
CLUSTER_DEMONSTRATED | genbank:EF159954.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000975 | MIBIG | 5 |
This page is generated from data/natural_products/unclassified/cryptophycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.