NaturalProductMech

α-cyclopiazonic acid

CHEBI:17734 EXACT SEEDED

Structure

Standard InChIKeyCNZIQHGDUXRUJS-PTNHGACKSA-N
SMILESO/C(C)=C(C1=O)/C([C@](N1C2(C)C)([H])[C@@]([C@@]2([H])C3)([H])C4=CNC5=CC=CC3=C54)=O
Stereochemistryfully defined

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Aspergillus flavus
NCBITaxon:5059
BGC_CHARACTERIZED mibig:BGC0001874 DOI:10.1016/0040-4020(68)88113-x

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus tamarii
NCBITaxon:41984
LOTUS DOI:10.1016/S0040-4020(03)00413-7
Penicillium griseofulvum
NCBITaxon:5078
LOTUS DOI:10.1039/P19810003292
Aspergillus flavus
NCBITaxon:5059
LOTUS DOI:10.1007/S10600-009-9433-8

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001874 Aspergillus flavus
NCBITaxon:5059
CLUSTER_DEMONSTRATED genbank:JN712211.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001874MIBIG4
CHEBI:17734CHEBI3-star

This page is generated from data/natural_products/unclassified/cyclopiazonic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.