NaturalProductMech

daptomycin

naturalproductmech:mibig-d4998c3d5b MINTED SEEDED

Structure

Standard InChIKeyDOAKLVKFURWEDJ-QCMAZARJSA-N
SMILESCCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]3[C@H](OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)[C@H](C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C
Stereochemistryfully defined
Cross-referencespubchem:21585658

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces filamentosus NRRL 11379
NCBITaxon:457430
SOURCE_ASSERTION mibig:BGC0000336 PMID:15870461

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces filamentosus
NCBITaxon:67294
LOTUS DOI:10.1099/MIC.0.27757-0

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000336 Streptomyces filamentosus NRRL 11379
NCBITaxon:457430
CLUSTER_UNSTATED genbank:AY787762.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000336MIBIG5

This page is generated from data/natural_products/unclassified/daptomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.