NaturalProductMech

endopyrrole A

naturalproductmech:mibig-3749610d08 MINTED SEEDED

Structure

Standard InChIKeyKRMWEQCPKUMYBI-DKKFUSLWSA-N
SMILESCC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)C1=CC=C[NH]1)C(C)C)C(=O)N[C@@H](C(=O)N[C@@H]1C(=O)N[C@H](CO)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)O[C@@H]1C)C(C)C
Stereochemistryfully defined
Cross-referencesnpatlas:NPA032899

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Mycetohabitans rhizoxinica HKI 454
NCBITaxon:882378
BGC_CHARACTERIZED mibig:BGC0002048 PMID:21131495
Mycetohabitans rhizoxinica
NCBITaxon:412963
BGC_CHARACTERIZED mibig:BGC0002326 PMID:31283172

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Burkholderia rhizoxinica
NCBITaxon:412963
LOTUS DOI:10.1021/ACSCHEMBIO.9B00406

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002048 Mycetohabitans rhizoxinica HKI 454
NCBITaxon:882378
CLUSTER_DEMONSTRATED genbank:FR687359.1
mibig:BGC0002326 Mycetohabitans rhizoxinica
NCBITaxon:412963
CLUSTER_DEMONSTRATED genbank:MN081797.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002048, BGC0002326. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002048MIBIG3
BGC0002326MIBIG2

This page is generated from data/natural_products/unclassified/endopyrrole-a.yaml, which is generated from the committed inventories. Neither is edited by hand.