equisetin
naturalproductmech:mibig-4b83bfc007 MINTED SEEDED cytotoxic
Structure
| Standard InChIKey | QNQBPPQLRODXET-AIMHRHHOSA-N |
|---|---|
| SMILES | [H][C@@]12C[C@H](C)CC[C@@]1([H])[C@@](C)([C@H](\C=C\C)C=C2)C(\O)=C1\C(=O)[C@H](CO)N(C)C1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA013853, pubchem:54684703 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fusarium heterosporum NCBITaxon:42747 |
SOURCE_ASSERTION | mibig:BGC0001255 | DOI:10.3390/md20110656 |
Occurrences 8
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Saccharopolyspora erythraea NCBITaxon:1836 |
LOTUS | DOI:10.1021/NP400761G |
| Fusarium pallidoroseum NCBITaxon:298378 |
LOTUS | DOI:10.1021/NP400761G |
| Ferula equisetacea NCBITaxon:371341 |
LOTUS | DOI:10.1007/BF00567157 |
| Fusarium equiseti NCBITaxon:61235 |
LOTUS | DOI:10.1021/JA00203A025 |
| Fusarium heterosporum NCBITaxon:42747 |
LOTUS | DOI:10.1016/0040-4039(96)01844-8 |
| Fusarium heterosporum NCBITaxon:42747 |
LOTUS | DOI:10.1016/S0040-4039(98)00269-X |
| Fusarium heterosporum NCBITaxon:42747 |
LOTUS | DOI:10.1021/CB400159F |
| Fusarium heterosporum NCBITaxon:42747 |
LOTUS | DOI:10.1177/095632029901000202 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001255 | Fusarium heterosporum NCBITaxon:42747 |
CLUSTER_UNSTATED | genbank:KC439347.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Ovarian cell line, single concentration | ACTIVE | pubchem.aid:1794790 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001255 | MIBIG | 4 |
This page is generated from data/natural_products/unclassified/equisetin.yaml, which is generated from the committed inventories. Neither is edited by hand.