NaturalProductMech

fengycin

naturalproductmech:mibig-cb97dd2f5e MINTED SEEDED

Structure

Standard InChIKeyCUOJDWBMJMRDHN-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCC(CC(=O)NC(CCC(=O)O)C(=O)NC(CCCN)C(=O)NC1CC2=CC=C(C=C2)OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C3CCCN3C(=O)C(NC(=O)C(NC(=O)C(NC1=O)C(C)O)CCC(=O)O)C)CCC(=O)N)CC4=CC=C(C=C4)O)C(C)CC)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:443591, npatlas:NPA020186, pubchem:5491283

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Bacillus velezensis FZB42
NCBITaxon:326423
BGC_CHARACTERIZED mibig:BGC0001095 PMID:14762003
Bacillus subtilis subsp. subtilis
NCBITaxon:135461
SOURCE_ASSERTION mibig:BGC0000407 PMID:22614917

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Bacillus
NCBITaxon:1386
LOTUS DOI:10.1021/NP300574V
Bacillus velezensis
NCBITaxon:492670
LOTUS DOI:10.1128/JB.186.4.1084-1096.2004

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0001095 Bacillus velezensis FZB42
NCBITaxon:326423
CLUSTER_DEMONSTRATED genbank:CP000560.1
mibig:BGC0000407 Bacillus subtilis subsp. subtilis
NCBITaxon:135461
CLUSTER_UNSTATED genbank:JQ073773.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000407, BGC0001095. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001095MIBIG5
BGC0000407MIBIG5

This page is generated from data/natural_products/unclassified/fengycin.yaml, which is generated from the committed inventories. Neither is edited by hand.