NaturalProductMech

frontalamide B

naturalproductmech:mibig-bb1d7e8cf9 MINTED SEEDED

Structure

Standard InChIKeyFHESOIDVDRLWJU-VHQOODOSSA-N
SMILESC[C@H]1[C@H](C[C@H]2[C@@H]1[C@H]3[C@H](C2)[C@H]4C/C=C\C(=O)NCCC(C5C(=O)C(=C(/C=C/[C@@H]4CC3=O)O)C(=O)N5)O)C=C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:101515038

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. SPB78
NCBITaxon:591157
BGC_CHARACTERIZED mibig:BGC0000996 PMID:20547882

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1073/PNAS.1001513107

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000996 Streptomyces sp. SPB78
NCBITaxon:591157
CLUSTER_DEMONSTRATED genbank:GG657742.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000996MIBIG5

This page is generated from data/natural_products/unclassified/frontalamide-b.yaml, which is generated from the committed inventories. Neither is edited by hand.