NaturalProductMech

hapalosin A

naturalproductmech:mibig-f35b98ab86 MINTED SEEDED

Structure

Standard InChIKeyNJNAHFYVTBZQHU-LFFUDGMSSA-N
SMILESCCCCCCC[C@H]1OC(=O)C[C@@H](O)[C@H](CC2=CC=CC=C2)N(C)C(=O)[C@@H](OC(=O)[C@H]1C)C(C)C
Stereochemistryfully defined
Cross-referencespubchem:133055, cyanometdb:CyanoMetDB_1323, npatlas:NPA019174

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fischerella sp. PCC 9431
NCBITaxon:1173023
SOURCE_ASSERTION mibig:BGC0001467 DOI:10.1021/jo00103a011

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fischerella
NCBITaxon:1190
LOTUS DOI:10.1021/JO00103A011
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JA00101A015
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JO00103A011
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JO00117A017
Hapalosiphon welwitschii
NCBITaxon:162986
CYANOMETDB DOI:10.1021/jo00103a011

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001467 Fischerella sp. PCC 9431
NCBITaxon:1173023
CLUSTER_DEMONSTRATED genbank:NZ_KE650771.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001467MIBIG5

This page is generated from data/natural_products/unclassified/hapalosin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.