heronamide A
naturalproductmech:mibig-d2f2523cbc MINTED SEEDED
Structure
| Standard InChIKey | APYNVIXJDXCVNV-RAAOCQATSA-N |
|---|---|
| SMILES | [H][C@]12\C=C/C=C(C)/[C@@]3([H])[C@H](O)[C@H](O)C=C[C@]3([H])\C=C(C)\[C@@]1([H])[C@]1([H])[C@@H](O)C[C@@H](C\C=C\C=C\CCC)N1C2=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA02271, pubchem:102257463, npatlas:NPA002271 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. SCSIO 03032 NCBITaxon:2878388 |
SOURCE_ASSERTION | mibig:BGC0001349 | PMID:26194087 |
| Streptomyces sp. CMB-0406 CBM-0406 NCBITaxon:1826667 |
SOURCE_ASSERTION | mibig:BGC0002101 | PMID:27091090 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1039/C0OB00267D |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001349 | Streptomyces sp. SCSIO 03032 NCBITaxon:2878388 |
CLUSTER_UNSTATED | genbank:KP742963.1 |
| mibig:BGC0002101 | Streptomyces sp. CMB-0406 CBM-0406 NCBITaxon:1826667 |
CLUSTER_UNSTATED | genbank:LT548273.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001349, BGC0002101. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001349 | MIBIG | 5 |
| BGC0002101 | MIBIG | 3 |
This page is generated from data/natural_products/unclassified/heronamide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.