NaturalProductMech

ilicicolin B

CHEBI:146153 EXACT SEEDED antimicrobial unspecified

An ilicicolin that is 2,4-dihydroxy-6-methyl-benzaldehyde which is substituted at position 3 by a (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl group.

Structure

Standard InChIKeyQAPOXOGEDXIOHD-VZRGJMDUSA-N
SMILESCC1=CC(=C(C(=C1C=O)O)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O
Stereochemistryfully defined
Cross-referencespubchem:10405997

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Stachybotrys bisbyi
NCBITaxon:80385
SOURCE_ASSERTION mibig:BGC0001390 DOI:10.1016/j.bbabio.2008.11.016

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Albatrellus ovinus
NCBITaxon:139090
LOTUS DOI:10.1016/S0223-5234(97)89088-5
Neonectria coccinea
NCBITaxon:57153
LOTUS DOI:10.1039/P19720002136

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001390 Stachybotrys bisbyi
NCBITaxon:80385
CLUSTER_UNSTATED genbank:LC125467.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Open questions 1

name-disagreement — ChEBI calls this structure 'ilicicolin B' and MIBiG calls it 'LL-Z1272beta'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.

Provenance

Source conceptSourceVersion
BGC0001390MIBIG3
CHEBI:146153CHEBI3-star

This page is generated from data/natural_products/unclassified/ilicicolin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.