NaturalProductMech

kirromycin

naturalproductmech:mibig-9aabe14e89 MINTED SEEDED

Structure

Standard InChIKeyHMSYAPGFKGSXAJ-PAHGNTJYSA-N
SMILESCC[C@H](C(=O)NC/C=C/C=C(\C)/[C@H]([C@@H](C)[C@H]1[C@H]([C@H]([C@H](O1)/C=C/C=C/C=C(\C)/C(=O)C2=C(C=CNC2=O)O)O)O)OC)[C@@]3([C@@H]([C@@H](C([C@@H](O3)/C=C/C=C\C)(C)C)O)O)O
Stereochemistryfully defined
Cross-referencespubchem:54697674, npatlas:NPA024864

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces collinus Tu 365
NCBITaxon:1214242
BGC_CHARACTERIZED mibig:BGC0001070 DOI:10.1002/mrc.1260270807

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Actinoplanes
NCBITaxon:1865
LOTUS DOI:10.7164/ANTIBIOTICS.46.1175
Streptomyces collinus
NCBITaxon:42684
LOTUS DOI:10.1007/S10295-015-1685-7
Streptomyces collinus
NCBITaxon:42684
LOTUS DOI:10.1021/ACSCHEMBIO.9B00086

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001070 Streptomyces collinus Tu 365
NCBITaxon:1214242
CLUSTER_DEMONSTRATED genbank:AM746336.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001070MIBIG5

This page is generated from data/natural_products/unclassified/kirromycin.yaml, which is generated from the committed inventories. Neither is edited by hand.