NaturalProductMech

lactonamycin Z

naturalproductmech:mibig-2b2384b902 MINTED SEEDED

Structure

Standard InChIKeyFUPCTCUEYKCRGQ-UHFFFAOYSA-N
SMILESCOC12CC(=O)OC11C(=O)C3=C(O)C4=C5CN(C)C(=O)C5=C(O)C=C4C=C3C(=O)C1(CO2)OC1CC(O)C(O)C(C)O1
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA08323

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sanglieri
NCBITaxon:193460
SOURCE_ASSERTION mibig:BGC0000237 PMID:18070976

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces sanglieri
NCBITaxon:193460
LOTUS DOI:10.7164/ANTIBIOTICS.56.1058

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000237 Streptomyces sanglieri
NCBITaxon:193460
CLUSTER_UNSTATED genbank:EU147299.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000237MIBIG5

This page is generated from data/natural_products/unclassified/lactonamycin-z.yaml, which is generated from the committed inventories. Neither is edited by hand.