NaturalProductMech

Largimycin A3

naturalproductmech:mibig-167cd23557 MINTED SEEDED

Structure

Standard InChIKeySRTHRTWGDJJGDY-YWAQVVFGSA-N
SMILESC[C@@]12/C=C/C(=O)/C=C/C=C\C3=COC(=N3)/C([C@H](O)CCl)=N\OC(=O)C[C@@]([C@@]3(C(=O)O)CO3)(CC1)S2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA032050

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces argillaceus
NCBITaxon:41951
BGC_CHARACTERIZED mibig:BGC0001853 DOI:10.1021/acschembio.0c00160

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces argillaceus
NCBITaxon:41951
LOTUS DOI:10.1021/ACSCHEMBIO.0C00160

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001853 Streptomyces argillaceus
NCBITaxon:41951
CLUSTER_DEMONSTRATED genbank:LR131959.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001853MIBIG3

This page is generated from data/natural_products/unclassified/largimycin-a3.yaml, which is generated from the committed inventories. Neither is edited by hand.