lysocin E
naturalproductmech:mibig-d34d870776 MINTED SEEDED antibacterial
Structure
| Standard InChIKey | QJPVBLGWZKAQRW-BQBICWQZSA-N |
|---|---|
| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC2=C[NH]C3=CC=CC=C23)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC2=CC=CC=C2)N(C)C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)C[C@H](O)CC(C)C)[C@@H](C)OC(=O)[C@H]([C@@H](C)O)NC1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA032822 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Lysobacter sp. NCBITaxon:72226 |
BGC_CHARACTERIZED | mibig:BGC0002384 | PMID:32610008 |
| Lysobacter sp. RH2180-5 NCBITaxon:1809648 |
SOURCE_ASSERTION | mibig:BGC0001657 | PMID:27553855 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Lysobacter NCBITaxon:68 |
LOTUS | DOI:10.1021/ACSSYNBIO.0C00067 |
| Lysobacter NCBITaxon:68 |
LOTUS | DOI:10.1038/JA.2016.102 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002384 | Lysobacter sp. NCBITaxon:72226 |
CLUSTER_DEMONSTRATED | genbank:MT410681.1 |
| mibig:BGC0001657 | Lysobacter sp. RH2180-5 NCBITaxon:1809648 |
CLUSTER_UNSTATED | genbank:LC128664.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-b6c9cc2b59 (same structure, same inchikey)
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001657, BGC0002384. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002384 | MIBIG | 3 |
| BGC0001657 | MIBIG | 4 |
This page is generated from data/natural_products/unclassified/lysocin-e.yaml, which is generated from the committed inventories. Neither is edited by hand.