NaturalProductMech

mutanocyclin

naturalproductmech:mibig-5265fbfee5 MINTED SEEDED

Structure

Standard InChIKeySHHAXAUQMPMPRV-SSDOTTSWSA-N
SMILESCC(=O)C1=C(O)[C@@H](CC(C)C)NC1=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA027195, pubchem:54683942

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptococcus mutans
NCBITaxon:1309
BGC_CHARACTERIZED mibig:BGC0002287 PMID:31413323
Streptococcus mutans B04Sm5
NCBITaxon:1225197
BGC_CORRELATED mibig:BGC0002058 PMID:25576609

Occurrences 0

None cited.

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002287 Streptococcus mutans
NCBITaxon:1309
CLUSTER_DEMONSTRATED genbank:MK144293.1
mibig:BGC0002058 Streptococcus mutans B04Sm5
NCBITaxon:1225197
CLUSTER_CORRELATED genbank:NZ_ALYY01000026.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002058, BGC0002287. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002287MIBIG2
BGC0002058MIBIG3

This page is generated from data/natural_products/unclassified/mutanocyclin.yaml, which is generated from the committed inventories. Neither is edited by hand.