nannocystin a
naturalproductmech:mibig-038ee07fcc MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | PEOAVEOEVIQCMT-XWDGXJISSA-N |
|---|---|
| SMILES | C[C@@H](CC)[C@@H]1N(C([C@@]2(C)[C@H](C[C@H](/C(C)=C/C=C/[C@H]([C@@H](C3=CC=CC=C3)OC([C@H](C(O)(C)C)NC([C@H](NC1=O)CC4=CC(Cl)=C(O)C(Cl)=C4)=O)=O)C)OC)O2)=O)C |
| Stereochemistry | fully defined |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Nannocystis sp. MB1016 NCBITaxon:1696011 |
SOURCE_ASSERTION | mibig:BGC0001212 | PMID:26179970 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nannocystis NCBITaxon:53 |
LOTUS | DOI:10.1002/ANIE.201411377 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001212 | Nannocystis sp. MB1016 NCBITaxon:1696011 |
CLUSTER_UNSTATED | genbank:KT067736.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001212 | MIBIG | 4 |
This page is generated from data/natural_products/unclassified/nannocystin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.