penitrem B
naturalproductmech:mibig-5ffdb106c9 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | CRPJNVUYZRFGAK-WKAGVDCZSA-N |
|---|---|
| SMILES | [H][C@]12C[C@@]3([H])[C@@]1([H])C1=C(CC2=C)C=CC2=C1C1=C(N2)[C@@]2(C)[C@@]([H])(CC[C@@]4(O)[C@@]56O[C@@H]5[C@@H](O)[C@H](O[C@@]6([H])CC[C@]24C)C(C)=C)[C@]1([H])OC3(C)C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA03988, pubchem:3084087 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium simplicissimum NCBITaxon:69488 |
SOURCE_ASSERTION | mibig:BGC0001375 | DOI:10.1021/jf00030a027 |
Occurrences 11
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Mucor irregularis NCBITaxon:1290454 |
LOTUS | DOI:10.1021/ACS.JNATPROD.6B00403 |
| Aspergillus sulphureus NCBITaxon:138284 |
LOTUS | DOI:10.1021/JO00033A030 |
| Penicillium crustosum NCBITaxon:36656 |
LOTUS | DOI:10.1021/JF020983E |
| Penicillium crustosum NCBITaxon:36656 |
LOTUS | DOI:10.1039/P19830001847 |
| Penicillium crustosum NCBITaxon:36656 |
LOTUS | DOI:10.1039/P19830001857 |
| Penicillium crustosum NCBITaxon:36656 |
LOTUS | DOI:10.1039/P19830001863 |
| Penicillium verrucosum NCBITaxon:60171 |
LOTUS | DOI:10.1021/NP50109A017 |
| Penicillium solitum NCBITaxon:60172 |
LOTUS | DOI:10.1021/JF020983E |
| Penicillium solitum NCBITaxon:60172 |
LOTUS | DOI:10.1039/P19830001847 |
| Penicillium solitum NCBITaxon:60172 |
LOTUS | DOI:10.1039/P19830001857 |
| Penicillium solitum NCBITaxon:60172 |
LOTUS | DOI:10.1039/P19830001863 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001375 | Penicillium simplicissimum NCBITaxon:69488 |
CLUSTER_UNSTATED | genbank:LC027937.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001375 | MIBIG | 4 |
This page is generated from data/natural_products/unclassified/penitrem-b.yaml, which is generated from the committed inventories. Neither is edited by hand.