NaturalProductMech

phosphonoacetic acid

CHEBI:15732 EXACT SEEDED antiviral

A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.

Structure

Standard InChIKeyXUYJLQHKOGNDPB-UHFFFAOYSA-N
SMILESC(C(=O)O)P(=O)(O)O
Stereochemistryfully defined

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. NRRL F-525
NCBITaxon:1463861
SOURCE_ASSERTION mibig:BGC0001739 DOI:10.1111/j.1749-6632.1977.tb21966.x

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1074/JBC.M605449200

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001739 Streptomyces sp. NRRL F-525
NCBITaxon:1463861
CLUSTER_UNSTATED genbank:NZ_JNXE01000019.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0001739MIBIG3
CHEBI:15732CHEBI3-star

This page is generated from data/natural_products/unclassified/phosphonoacetic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.