pulcherriminic acid
CHEBI:71599 EXACT SEEDED
A pyrazine N-oxide that is pyrazine-1,4-dioxide substituted at positions 2 and 5 by hydroxy groups and at positions 3 and 6 by isobutyl groups. Formed by oxidative aromatisation of cyclo(L-leucyl-L-leucyl).
Structure
| Standard InChIKey | WXWWNANFOZVVLD-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(C)CC1=C(O)N(=O)=C(CC(C)C)C(O)=N1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA012181 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Metschnikowia aff. pulcherrima NCBITaxon:2163413 |
BGC_CORRELATED | mibig:BGC0002321 | PMID:31081214 |
| Bacillus subtilis subsp. subtilis str. 168 NCBITaxon:224308 |
SOURCE_ASSERTION | mibig:BGC0002103 | DOI:10.1038/s41522-023-00418-z |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Metschnikowia pulcherrima NCBITaxon:27326 |
LOTUS | DOI:10.1139/V63-021 |
| Caesalpinia pulcherrima NCBITaxon:53846 |
LOTUS | DOI:10.1016/S0031-9422(00)97708-2 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002321 | Metschnikowia aff. pulcherrima NCBITaxon:2163413 |
CLUSTER_CORRELATED | genbank:CP034458.1 |
| mibig:BGC0002103 | Bacillus subtilis subsp. subtilis str. 168 NCBITaxon:224308 |
CLUSTER_DEMONSTRATED | genbank:NC_000964.3 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0002103, BGC0002321. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002321 | MIBIG | 3 |
| BGC0002103 | MIBIG | 2 |
| CHEBI:71599 | CHEBI | 3-star |
This page is generated from data/natural_products/unclassified/pulcherriminic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.