NaturalProductMech

retimycin A

naturalproductmech:mibig-63bd8ae7bd MINTED SEEDED

Structure

Standard InChIKeyKDRVEKPMWVHCOU-UHFFFAOYSA-N
SMILESO=C(NC1C(NC(C)C(N(C)C2C(N(C)C3(C(C)C3)C(OC(C)C(NC(C4=NC5=CC=CC=C5C=C4O)=O)C(NC(C)C(N(C)C(C(S(C)=O)SC2)C(N(C)C6(C(C)C6)C(OC1C)=O)=O)=O)=O)=O)=O)=O)=O)C7=NC8=CC=CC=C8C=C7O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Salinispora arenicola CNT005
NCBITaxon:1137255
SOURCE_ASSERTION mibig:BGC0001228 PMID:25865308

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001228 Salinispora arenicola CNT005
NCBITaxon:1137255
CLUSTER_UNSTATED genbank:NZ_KI911494.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001228MIBIG5

This page is generated from data/natural_products/unclassified/retimycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.