roquefortine D
naturalproductmech:mibig-b9286d993c MINTED SEEDED
Structure
| Standard InChIKey | IQVNREJWRXOHEO-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(C)(C=C)C12CC3N(C1NC1=CC=CC=C21)C(=O)C(CC1=CN=CN1)NC3=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA010085 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium rubens Wisconsin 54-1255 NCBITaxon:500485 |
BGC_CHARACTERIZED | mibig:BGC0000420 | DOI:10.1371/journal.pone.0065328 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Penicillium roqueforti NCBITaxon:5082 |
LOTUS | DOI:10.1271/BBB1961.42.2387 |
| Fusarium NCBITaxon:5506 |
LOTUS | DOI:10.1271/BBB1961.42.2387 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000420 | Penicillium rubens Wisconsin 54-1255 NCBITaxon:500485 |
CLUSTER_DEMONSTRATED | genbank:AM920436.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000420 | MIBIG | 5 |
This page is generated from data/natural_products/unclassified/roquefortine-d.yaml, which is generated from the committed inventories. Neither is edited by hand.